Hillsboro is a city in and the county seat of Highland County, Ohio, United States. The population was 6,605 at the 2010 census.
Hillsboro was platted in 1807, and most likely named for the hills near the original town site.
According to the United States Census Bureau, the city has a total area of 5.43 square miles (14.06 km²), all land.
As of the census of 2010, there were 6,605 people, 2,755 households, and 1,612 families residing in the city. The population density was 1,216.4 inhabitants per square mile (469.7/km²). There were 3,181 housing units at an average density of 585.8 per square mile (226.2/km²). The racial makeup of the city was 90.0% White, 5.8% African American, 0.3% Native American, 0.8% Asian, 0.2% from other races, and 2.9% from two or more races. Hispanic or Latino of any race were 1.3% of the population.
There were 2,755 households of which 30.5% had children under the age of 18 living with them, 37.7% were married couples living together, 16.5% had a female householder with no husband present, 4.3% had a male householder with no wife present, and 41.5% were non-families. 37.1% of all households were made up of individuals and 18.2% had someone living alone who was 65 years of age or older. The average household size was 2.28 and the average family size was 2.97.
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